The meaning of MAIN is physical strength : force —used in the phrase with might and main. How to use main in a sentence.

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MAIN definition: 1. larger, more important, or having more influence than others of the same type: 2. a large pipe…. Learn more.

chief in size, extent, importance, etc.; principal; leading; specif., designating a large central unit on which subsidiaries or branches depend the main post office

main (meɪn) adj (prenominal) 1. chief or principal in rank, importance, size, etc 2. sheer or utmost (esp in the phrase by main force)

Originating from Old English mægen, meaning "power, strength, force," derived from Proto-Germanic *maginam and PIE root *magh- "to have power."

Main definition: Most important; principal.

physical strength, power, or force: to struggle with might and main. the chief or principal part or point: The main of their investments was lost during the war.

main, n.¹ meanings, etymology, pronunciation and more in the Oxford English Dictionary

Synonyms for MAIN: primary, predominant, greatest, highest, dominant, foremost, first, big; Antonyms of MAIN: last, least, minor, secondary, slight, unimportant, trivial, insignificant