For adults with chronic low back pain, gabapentin prescription is associated with an increased risk for dementia and mild cognitive impairment (MCI).

Only 34% of patients with erythema migrans >5 cm are positive for Lyme disease by a standard two-tier testing (STTT) algorithm.

The table below is a review of notable updates that occurred in June 2025 for investigational products in development (not an inclusive list). Click on the status to view our full coverage.

Individuals who report being always lonely have significantly higher predicted probability of depression. HealthDay News — Loneliness is a predictor of depression and poor health outcomes, according ...

Patients with ID receiving TNF inhibitors are at greater risk for cutaneous malignancy than patients who are biologic-naïve.

Major and minor relapses are relatively common in GCA and primarily occur within the first 2 years of diagnosis.

The introduction of immune checkpoint inhibitors (ICIs) was associated with a widening survival disparity between those with private insurance and those without health insurance.

Lifestyle interventions may improve oxidative and lipid metabolism among older adults with RA and overweight/obesity.

The prevalence of frailty was 33% among a US-wide cohort of patients with RMDs, with the highest rates found among those with fibromyalgia or CTDs.

The European Association for the Study of Obesity (EASO) framework may offer a more sensitive measure of obesity than traditional body mass index (BMI).

Compared with other interventions, GNB was effective for pain relief and functional improvement among patients with knee OA.

The denosumab biosimilars Stoboclo (denosumab-bmwo) and Osenvelt (denosumab-bmwo) are now commercially available in the US, according to Celltrion.