There were significant associations between echocardiographic parameters, such as increased left ventricular mass and greater interventricular septal thickness at end-diastole, and positive 99mTc-PYP ...

At the time of diagnosis, patients with different types of [cardiac amyloidosis] had distinct echocardiographic presentation and survival differed in the first 3 years. Differences in ...

Tetrabenazine and olanzapine treatment led to significant improvements in chorea but olanzapine also increased rigidity. Olanzapine improves chorea, irritability, and behavior in patients with ...

The short-supervised group used CPAP fewer hours per night and had lower adherence adjusted for age-specific sleep needs. Two different strategies for continuous positive airway pressure (CPAP) ...

Rare Disease Advisor, a trusted source of medical news and feature content for healthcare providers, offers clinicians insight into the latest research to inform clinical practice and improve patient ...

Seladelpar treatment was significantly associated with an increased normalization in the levels of alkaline phosphatase, a biomarker of cholestasis, in patients with primary biliary cholangitis (PBC).

A monocyte mitochondrial superoxide cutoff accurately stratified short-term survival risk in hepatocellular carcinoma. Circulating leukocyte mitochondrial oxidative stress may be a protective ...

Despite his kappa-restricted gammopathy and suspicion of AL amyloidosis, further investigation yielded the accurate diagnosis. Transthyretin amyloid cardiomyopathy (ATTR-CM) can present with a ...

CLL-related immune dysfunction, along with therapy-associated immunosuppression, contributes to impaired tumor surveillance. Patients with chronic lymphocytic leukemia (CLL) are at increased risk for ...

Several guidelines have been developed for the diagnosis and management of Fabry disease. The focus of treatment is preserving organ function, maximizing quality of life, and normalizing life ...

The association between the reduction in 99m Tc-DPD uptake at follow-up and several established biomarkers of response to treatment in transthyretin amyloid cardiomyopathy (ATTR-CM) is poor, according ...

The mean time a healthcare professional and patients spent for all enzyme replacement therapy-related activities was 2.5 hours and 6.1 hours, respectively. A new multiregional study published in the ...