Gene therapy with elivaldogene autotemcel (eli-cel) consisting of autologous CD34+ cells transduced with lentiviral vector containing ABCD1 complementary DNA (Lenti-D ...

New data show that the United States continues to fall short when it comes to both protecting the health of individual people and promoting societal well-being. From the Harvard T.H. Chan School ...

Dr. Danielle C. Crabtree (Medicine): A 37-year-old man was admitted to this hospital because of fever, myalgia, jaundice, and hypoxemia. The patient had been healthy until 9 days before this ...

Treatments for Dupuytren’s contracture include limited fasciectomy and collagenase injection. Comparisons of the effectiveness of these treatments have been limited. We performed an unblinded ...

More than 30 years ago, the first transplantation with autologous hematopoietic stem cells modified with integrated murine retroviral vectors carrying potentially therapeutic genes was performed ...

Reductions in the estimated number of new HIV infections in the United States have overshadowed disconcerting trends among Latino people. Increased visibility, political will, and resources are ...

A 25-year-old woman receiving daily prednisolone treatment for systemic lupus erythematosus presented with a 3-month history of erosive, violaceous plaques in the antecubital fossae, popliteal ...

In this randomized trial, conducted between 1989 and 2022 to compare radical prostatectomy with watchful waiting, radical prostatectomy led to a 48% lower risk of death from prostate cancer and to ...

Hairy-cell leukemia, a rare B-cell cancer driven by a BRAF mutation and manifesting with cytopenias and splenomegaly, is responsive to purine analogue chemotherapy and to BRAF inhibitors combined ...

To the Editor: Hengel et al. (Aug. 1 issue) 1 claim to have shown “autoantibodies targeting nephrin in podocytopathies.” However, at no point do they directly show antinephrin autoantibodies ...

U.S. states, which are better positioned than the federal government to precisely and comprehensively address the drivers of low-value health care spending, should lead the way in establishing ...