Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular ...

Semaglutide at a dose of 2.4 mg has established weight-loss and cardiovascular benefits, and cagrilintide at a dose of 2.4 mg ...

Explore a collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary.

Corporatization” of health care, a process predicted decades ago, now refers to the general trend throughout the industry toward higher levels of integrated control by consolidated profit-seeking ...

Explore the current issue of The New England Journal of Medicine (Vol. 393 No. 1).

In this NEJM Outbreaks Update, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by Indiana Commissioner of Public Health Lindsay Weaver to discuss the current state of avian in ...

Chronic meningitis is broadly characterized as infectious or noninfectious (Table 1). Geographic region of residence, travel, immune status, and underlying illnesses are the initial building ...

Age-related hearing loss is characterized by the progressive loss of the sensory hair cells of the inner ear, which are responsible for encoding sound into neural signals. 1,2 Unlike other cells ...

In the emergency department, the patient described the pain as sharp and rated it at 8 on a scale of 0 to 10 (with 10 indicating the most severe pain). The pain was worst in the epigastrium and in ...

Depression in adolescents is increasing at a greater rate than in adults. Change in appetite, loss of energy, and insomnia may be more apparent than mood changes. Pharmacologic treatment and psycho ...

Most rotator-cuff tears are degenerative, atraumatic, and more prevalent with age. Nonoperative treatment, including physical therapy, is typically recommended; surgery is considered in some cases.

The authors review the pathophysiology, revised diagnostic definitions, and management of acute kidney injury, a common condition in patients with cirrhosis.