Each journal is staffed by professional editors who work in collaboration with one another and our international Editorial Advisory Boards of leading scientists. Please feel free to contact any of the ...

EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

While only 1–2% of the human genome encodes proteins, the remaining repetitive, low-complexity part is poorly characterized, and was long referred to as “junk DNA” (ENCODE Project Consortium 2012; ...

Exhaustion of CD8 + T-cells leads to their reduced immune functionality and is controlled by numerous transcription factors. Here we show that the transcription factor IRF-5 helps to limit functional ...

imageimageThis study shows that small cell subpopulations experience transient, high-intensity mutational bursts, greatly increasing double mutation rates in wild-type yeast. These mutator episodes ...

This cover highlights the article Early coordination of cell migration and cardiac fate determination during mammalian gastrulation by Shayma Abukar, Kenzo Ivanovitch and colleagues. Using long-term ...

imageimageThis study identifies Ki-67 as a critical modulator of the intensity of pro-inflammatory gene expression governing neutrophil recruitment during respiratory infections. The severity of ...

Hematopoietic stem and progenitor cells (HSPCs) polarize in contact with the bone marrow stromal cells constituting their niche. Given the role of cell polarity in protection against tumorigenesis and ...

Histone posttranslational modifications (PTMs) such as ubiquitination, methylation and phosphorylation play a crucial role in gene transcription, DNA replication and repair (Chen and Tyler, 2022; ...

Brain metastasis (BM) remains a significant challenge in breast cancer (BC) management. While conventional metastatic routes primarily involve hematogenous dissemination, emerging evidence suggests ...

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