Key points The health implications of exposures to the Alberta oil sands are underresearched, despite more than a decade of calls from Indigenous communities and researchers for further investigation.

Background: Consent forms have become too long and often do little to help people understand the risk elements of their participation in research, instead focusing on risk reduction for research ...

Key points Dried plasma is dehydrated, powdered human plasma. Once mixed with sterile water, the reconstituted plasma delivers essential coagulation factors necessary for hemostasis and supports ...

Key points More than a decade after the launch of Canada’s Strategy for Patient-Oriented Research (SPOR), patient engagement is increasingly expected across the health research ecosystem.

Background: Race is a social construct reflecting broader systemic forces that can affect health, including mental health. We ...

BACKGROUND: An important aim of high tibial osteotomy (HTO) is to prevent or delay the need for total knee replacement (TKR). We sought to estimate the frequency and timing of conversion from HTO to ...

Background: Ground-level falls are common among older adults and are the most frequent cause of traumatic intracranial bleeding. The aim of this study was to derive a clinical decision rule that ...

BACKGROUND: The Global Burden of Disease Study represents a large and systematic effort to describe the burden of diseases and injuries over the past 3 decades. We aimed to summarize the Canadian data ...

Acne is one of the most burdensome diseases globally. 1, 2 Its prevalence among those aged 12 to 24 years is estimated to be 85%, although it can persist beyond young adulthood despite treatment. 3 – ...

Clinical practice guideline for management of osteoporosis and fracture prevention in Canada: 2023 update Hypertension Canada guideline for the diagnosis and treatment of hypertension in adults in ...

Bell palsy is an idiopathic weakness or paralysis of the face of peripheral nerve origin, with acute onset. It affects 20–30 persons per 100 000 annually, and 1 in 60 individuals will be affected over ...

Background: The prevalence of tuberculosis infection is critical to the design of tuberculosis prevention strategies, yet is unknown in Canada. We estimated the prevalence of tuberculosis infection ...