Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterised by multiorgan involvement.

Background SLE is an autoimmune disease that varies across ethnic populations and the regions that cause economic burdens, but nationwide epidemiological data for Thailand are lacking.Objective To ...

Systemic lupus erythematosus (SLE) imposes a great burden on the lives of patients. Patients’ and physicians’ concerns about the disease diverge considerably. Physicians focus on controlling disease ...

Background Interleukin-21 (IL-21) is a pleiotropic cytokine. Both IL-21 and the IL-21 receptor (IL-21R) have been shown to be upregulated in systemic lupus erythematosus (SLE). BOS161721, a humanized ...

Background/Purpose Belimumab was approved for the treatment of non-renal SLE in 2011 and has been previously associated with a lower risk of damage progression when compared with prior ‘usual care.’ ...

Objective Evaluate the impact of pregnancy physiology and medication non-adherence on serum hydroxychloroquine (HCQ) pharmacokinetics (PK) and exposure-response in SLE. Methods We conducted a PK ...

Objective The primary objective was to assess the prevalence of anti-ribosomal-P protein antibodies (anti-Rib-P) in a well-characterised Danish adult SLE cohort. Secondary objectives included (1) ...