2018 Meetings Abstracts: Fifth AACR-IASLC International Joint Conference: Lung Cancer Translational Science from the Bench to the Clinic January 8–11, 2018; San Diego, CA Proceedings: AACR Annual ...

Increased exon skipping, particularly affecting proteasome-related transcripts, was mediated by elevated serine/arginine-rich splicing factor 6 (SRSF6) levels in T-cell acute lymphoblastic leukemia.

Loss of the NFκB pathway inhibitor TRAF3 increased MHC-I expression, improving T cell–mediated cancer cell killing and tumor responsiveness to immune checkpoint blockade, an effect that could be ...

Colorectal cancers express abundant viral-like repeat elements that can be targeted by nucleoside reverse transcriptase inhibitors in preclinical models, which was further translated into a phase II ...

AbstractSummary:. Circulating tumor cells (CTC) are the source of metastases, but only an infinitesimal fraction of them eventually succeed in colonizing a distant organ. New results show that ...

Cancer cells reprogrammed into the myeloid lineage adopt an antigen-presenting cell phenotype and function, present endogenous tumor antigens, and stimulate robust antitumor immunity in hematologic ...

Cancer-associated fibroblasts (CAF) expressing Lrrc15, encoding a conserved transmembrane protein, increased in prevalence as mouse pancreatic cancer tumors progressed, and an LRRC15+ TGFβ CAF ...

2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 ...

1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 ...

AACR Journals Blood Cancer Discovery Cancer Discovery Cancer Epidemiology, Biomarkers & Prevention Cancer Immunology Research Cancer Prevention Research Cancer Research Cancer Research Communications ...

Abstract. The cell surface glycoprotein P-cadherin is highly expressed in a number of malignancies, including those arising in the epithelium of the bladder, breast, esophagus, lung, and upper ...

This study uncovers a role for OSMR in promoting ovarian cancer cell proliferation and metastasis by activating STAT3 signaling and demonstrates the preclinical efficacy of antibody-based OSMR ...