The San Francisco 49ers opened practice Wednesday for Sunday’s game against the Arizona Cardinals with 10 players (six starters) on the injury report, eight of whom did not practice. Quarterback Brock Purdy, who missed Sunday’s game against the Saints, was limited.

After their Super Bowl run, the 49ers were forced to replace Greenlaw, who tore his Achilles against the Kansas City Chiefs. Rather than elevating Winters, San Francisco turned to longtime Falcon De’Vondre Campbell. Despite posting solid numbers, Campbell was abruptly released by the end of week 14.

USA Today's NFL experts make their picks for a Week 3 showdown between the San Francisco 49ers and Arizona Cardinals

www.si.com/nfl/49ers How the 49ers can overcome their biggest problem by far East Grays Harbor Fire and Rescue says it had put out a car fire that was close to a building in the Murray Place neighborhood. Fire crews arrived on the scene of the fire at about 8:20 p.m.

A San Francisco 49ers’ trade pitch would see them land a Cleveland Browns star to help the tight end position amid George Kittle's injury.

Nick Saban gave Mac Jones high praise as he led the San Francisco 49ers to a win against the New Orleans Saints in Week 2.