Study reveals single-chain mRNA vaccines confer 100% protection against lethal mpox challenge in mice, marking a significant ...
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With viral outbreaks spreading more quickly, faster responses and quicker development of new vaccines has become crucial. However, production of the mRNA used in vaccines is hindered by its production ...
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高福和王奇慧团队基于结构生物学指导的疫苗研发平台,创新性地设计出嵌合三价mRNA疫苗。该疫苗在小鼠中可诱导出高效的体液免疫与细胞免疫,维持抗体水平在免疫近6个月后基本不变,实现了致死剂量痘苗病毒攻毒后对小鼠的完全保护,并可在猴痘病毒攻毒后降低小鼠多个器官中的病毒载量。相比之下,同样痘苗病毒剂量下,接种痘苗天坛株减毒活疫苗的小鼠全部死亡。
▎药明康德内容团队编辑  近年来,mRNA疫苗已经成为人类对抗疾病的全新工具。在COVID-19疫情期间,mRNA疫苗首次问世,为很多人带来了保护。2023年,诺贝尔生理学或医学奖也授予了mRNA疫苗领域的两位先驱——Katalin ...
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mRNA vaccines, pivotal in the fight against COVID-19, are now emerging as a promising innovation in cancer treatment. As ...
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