How long has it been since the Illini and Hoosiers met with so much at stake? Try October 1950, when No. 12 Illinois beat No. 19 Indiana 20-0 in Champaign.

Indiana football coach Curt Cignetti previewed Illinois and discussed quarterback Fernando Mendoza's progress, among other things, at his radio show Thursday.

Illinois all-conference defensive back Xavier Scott is likely to miss Saturday's Big Ten opener at No. 19 Indiana following an injury last week, coach Bret Bielema said Thursday.

Nebraska seeks to beat a Top 25 team for the first time in nine years when it puts its unbeaten record at stake against Michigan. The Cornhuskers have lost 27 straight games against Top 25 teams since beating No. 22 Oregon 35-32 on Sept. 17, 2016.

The Illini and Hoosiers' meeting is the biggest in series history – we know. But the season isn't over for the loser.

Nicole Auerbach and Joshua Perry break down what Illinois vs. Indiana in Week 4 will mean for the College Football Playoff and analyze the head coaching matchup between the two teams.

The defensive coordinators involved in Saturday's game could be leading college football programs of their own very soon