Maria Queralt Salas教授在报告开篇指出，allo-HCT作为一种潜在的根治性疗法，其适用人群正不断扩大，涵盖了更多高龄及伴有多种合并症的患者。这一趋势使得移植候选人群的异质性显著增加。传统的评估方法，如卡氏功能状态（Karnofsky Performance Status, KPS）评分，已难以全面捕捉患者的生理储备和抗压能力。

Researchers have found that patients with frailty and cardiometabolic diseases have increased risk for mortality.

Frailty is associated with higher odds of local and systemic postoperative complications among older women with nonmetastatic ...

Geroscience frames age-related diseases as being driven by ‘gerogenes,’ opening a path to gerotherapies that target ageing ...

A recent study published in the Journal of Stroke and Cerebrovascular Diseases revealed that frailty significantly worsens ...

Between 2006 and 2017, the percentage of patients with CLL/SLL receiving first-line treatment within 3 years of diagnosis ...

Social frailty in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) does not directly impact anxiety or depression but influences these conditions indirectly through ...

Gastrointestinal (GI) complications, such as postoperative ileus (POI) and intra-abdominal infections (IAI), remain a major ...

Higher potentially inappropriate medications were associated with an increased risk for frailty at diagnosis of cancer.

Unobserved differences in individual’s susceptibility to death are an important aspect in the analysis of contemporary mortality patterns. However, observed mortality rates at adult ages, which are ...