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You can even create custom functions using VBA. Python shines with its vast ecosystem of libraries. It’s an excellent choice for tasks that involve integrating Excel with other systems.
Microsoft is adding the Python programming language to Microsoft Excel, allowing users to create powerful functions for analyzing and manipulating data.
Microsoft today announced the public preview of Python in Excel, which will allow advanced spreadsheet users to combine scripts in the popular Python language and their usual Excel formulas in the ...
Python and Excel can only really talk to each other through limited functions—xl () and =PY ()—that can only return code results, not macros, VBA code, or other data, Microsoft claims.
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2 Actions to run script in Excel from Power Automate flows

Within Power Automate, it has been possible to run scripts in Excel using the Run Script action. Did you know that there is a ...
You can use command-line parameters to launch Microsoft Excel from the Run dialog box or by configuring the command and switches in a desktop shortcut.