Chlorpromazine, the first-line treatment of intractable hiccups, is contraindicated in PD. Baclofen could be considered as a first-line alternative. Conclusion: Although clozapine can be used to ...
He tried the same with the hiccupping patient and it worked. He then published his paper in 1988 “Termination of intractable hiccups with digital rectal massage” for which he won an IgNobel prize.