The portal protein gp20 of bacteriophage T4 is a dodecamer located at the special five-fold vertex of the viral capsid. Its functions are essential for head assembly, genome packaging, neck and tail ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...

DNA-encoded library (DEL) screening has become a standard tool in small-molecule drug discovery. Yet, even as its adoption ...

A piece that aired on NPR this week about the discovery of DNA's structure neglected to mention the significant contribution of Rosalind Franklin to that scientific milestone. And now some important ...

Could DNA be glycosylated? A new study published in Engineering explores this intriguing question, suggesting that DNA might undergo glycosylation, a process that could revolutionize our understanding ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

A tangle of DNA can look like a knotted ball in the cell nucleus. However, the genetic machinery has a complex and regulated ...

Neural networks are computing systems designed to mimic both the structure and function of the human brain. Caltech ...