Amplicon vectors 1 are HSV-1 particles identical to wild-type HSV-1 from the structural, immunological and host-range points of view, but which carry a concatemeric form of a DNA plasmid, named the ...

Herpes simplex virus type 1 (HSV-1) is a promising vehicle for gene transfer applications. HSV-1 is a large double-stranded DNA virus that can accommodate large or multiple transgene cassettes and ...