Two early games against Rams, return to MetLife Stadium and latest bye in franchise history as San Francisco chases return to ...

SANTA CLARA, Calif. -- If all goes according to plan between now and Sept. 12, defensive end Nick Bosa will be on the field and ready to play against the Detroit Lions in the San Francisco 49ers' ...

Brock Purdy quarterbacked the 49ers to a win over the Seahawks in Week 1, but will now miss time with a toe injury.

San Francisco tabbed Trey Lance over Jones in 2021 after a trade, with neither first-rounder panning out. Now, Jones will start in Brock Purdy's absence ...

Receiver Tee Higgins is also dealing with an ankle injury. They join the Niners in trying to manage a rash of injuries, including running back Trenton Cannon, who sustained a concussion on a scary hit ...

Mac Jones threw three touchdown passes in place of Brock Purdy and the 49ers improved to 2-0 with a 26-21 win at ...