Lonijaposides O–W have structural features that involve amino acid units sharing the N atom with a pyridinium (1 – 5) or nicotinic acid (6 – 9) moiety. The absolute configurations of the amino acid ...

Nicotinic receptors — a family of ligand-gated ion channels that mediate the effects of the neurotransmitter acetylcholine — are among the most well understood allosteric membrane proteins ...

Main The nicotinic acetylcholine (ACh) receptors have been objects of attention since Claude Bernard investigated the action of a Central American arrow poison (CURARE).