Some of the site's predictions differ from NFL Week 3 odds and other NFL Week 3 picks for NFL Week 3 games. How correct will the analytics be this week? Click on each game for more NFL Week 3 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.

Being winless is certainly a motivating factor to play your best, and factors like this should be considered before making Week 3 NFL predictions. If you are looking for NFL picks, NFL parlays, Fantasy football rankings or NFL DFS picks for Week 3,

Houston has one giveaway and CJ Stroud is the more trustworthy quarterback at 3-1 against Jacksonville in his young career. Over the last 14 meetings, Houston has won 12 versus Jacksonville. I grabbed the Texans at +1.5 for -112 odds and would go down to the ML as they could close as the favorite.

With the Pittsburgh Steelers headed to Foxborough for their Week 3 matchup against the New England Patriots in just a few days, here is the first look at Wednesday’s injury report. Legend: For up-to-date Steelers coverage,

Mike Florio and Chris Simms preview a Week 3 duel between the Steelers and Patriots at Gillette Stadium, detailing why "Pittsburgh's defense is going to start playing better football" against an iffy New England offense.

Pregame analysis and predictions of the Indianapolis Colts vs. Tennessee Titans NFL game to be played on September 21, 2025 on ESPN.

The Indianapolis Colts are off to their best start in more than a decade, but they face their first road game against the winless Tennessee Titans.