(23) However, SWE must be tested in rodent-based models to add its translational value. Therefore, we planned to investigate the neuroprotective effect of SWE against lipopolysaccharide (LPS)-induced ...

After spinal cord injury, lower urinary tract functions may be disrupted. Trans-rectal stimulation of the pudendal nerve may enable patients to regain these functions via minimally invasive means.

To our knowledge, to date, however, there are no widely utilized machine learning (ML) models that predict development of CLL. Therefore, the objective of this study was to leverage readily available ...

Recent structure-activity studies using a mutant mouse model of neuropathic pain have found that binding to α 2 -δ protein is a prerequisite for the analgesic actions of pregabalin. [12] ...

Neuropathic pain has no immediate cause. Research on a brain receptor may help stop this hard-to-treat condition by Pooja Shree Chettiar, Siddhesh Sabnis, The Conversation ...

Antagonism of the P2X3 receptor is one of the potential therapeutic strategies for the management of neuropathic pain because P2X3 receptors are predominantly localized on small to medium diameter C- ...

The AKR mouse—a mouse strain susceptible to development of hypertension and metabolic syndrome 190 —has been used to study the mechanisms underlying obesity-related pulmonary vascular remodeling in ...

Electrical signal transmission in conductive channels would entail the phenomenon of electromagnetic wave propagation. In nerve fibers, however, the established Hodgkin-Huxley model treats the ...

Damage to nerves at various levels of the peripheral and CNS will lead to sensory loss, but in a significant number of patients this is accompanied by a series of distressing painful signs and ...

To evaluate the performance and consistency of large language models (LLMs) across brand and generic oncology drug names in various clinical tasks, addressing concerns about potential fluctuations in ...

Adolore BioTherapeutics Announces Publication Demonstrating Biosafety and Efficacy of Kv7 Activating rdHSV-CA8* Analgesic Gene Therapy for Chronic Pain via the Intra-Articular Route in Mice ...