▎药明康德编者按：寡核苷酸疗法是一类近年来发展迅速的治疗模式。这类基于短核苷酸序列的新兴疗法能在RNA水平上调控基因转录与翻译，针对特定的致病突变实现靶向治疗。如今，已有超过20款寡核苷酸药物获得FDA批准，其中10款疗法在近5年获批，为多种罕见遗传 ...

They found that when mouse embryos develop to 7.75 days, a unique signaling domain appears at the embryo's inner-outer boundary -- the primordium determination zone.

近日，同济大学附属同济医院消化内科杨长青教授团队在Science子刊Science Translational Medicine（《科学·转化医学》）期刊上在线发表题为“Myeloid Mas-driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human ...