2025 Week 1 NFL picks, odds, best bets from proven model: This 5-way football parlay would return almost 25-1 After 10,000 simulations, SportsLine's model reveals its top Week 1 NFL 25-1 football ...

Before finalizing your 2025 Fantasy football draft strategy, be sure to check out the 2025 Fantasy football rankings and cheat sheets from the proven computer model at SportsLine.