In and of itself it doesn't mean much; sickle cell disease isn't exactly a major market. The fact that the U.S. Food and Drug Administration approved any CRISPR (clustered regularly interspaced short ...

Contributed by William G. Kaelin, Jr.; received May 3, 2024; accepted September 3, 2024; reviewed by M. Celeste Simon and Arul M. Chinnaiyan We designed CRISPR sgRNAs against murine Vhl, Pbrm1, Tsc1, ...

Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States Bioengineering Program, Georgia Institute of Technology, Atlanta, Georgia 30332, United ...

Research Center for Nanosensor Molecular Diagnostic & Treatment Technology, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong 518060, P. R. China Shenzhen ...

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like sickle cell, while also proving beyond doubt that chemical tags on DNA—often ...

CRISPR Therapeutics' recent in vivo CTX310 data validates its technology, marking a fundamental shift and supporting a rating upgrade from Sell to Hold. CASGEVY sales are growing but remain ...