TDP-43 Conference Marks Concerted Effort to Finally Snag Biomarkers. Add To My AlzForum; 30 Jun 2025. Steps Forward: Immunoassays for cryptic HDGFL2 flag TDP-43 proteinopathy in diverse disorders.

SORL1 RESEARCH MODELS ADDED. SORL1 knockout, knockin, and transgenic mice are now in the Research Models database. The database will be updated as more models become available.

Li-Huei Tsai, Massachusetts Institute of Technology, Boston, and colleagues some years ago turned light and sound into a therapy.They called it GENUS, short for gamma entrainment using sensory stimuli ...

This database is a repository of normal genetic variability, designed to be a tool for researchers who study neurodegenerative disease. It contains whole-exome sequencing results from nearly 500 ...

David Holtzman Washington University; Posted: 27 Jul 2018 The new data clearly showed that the anti-Aβ antibody BAN2401 was able to significantly remove amyloid from brain, as quantified by ...

A documentary of country legend Glen Campbell's life and “Goodbye Tour” following his diagnosis of Alzheimer's ...

28 Sep 2022. Eisai and Biogen yesterday announced positive topline results from the Phase 3 Clarity trial of their anti-amyloid antibody lecanemab.The drug slowed decline on the primary endpoint, ...

17 Aug 2018. After years of fits and starts, anti-amyloid immunotherapies are finally hitting their target effectively. At least four drugs have now demonstrated the ability to clear plaques from the ...

25 Jan 2024. Not so long ago, a blood test for Alzheimer’s disease seemed a pipe dream. Now, after years of study, the field is awash with sensitive assays that signal the proteopathic culprits Aβ and ...

22 Mar 2024. Old drugs die hard. Despite a string of negative Phase 3 trials, HMTM, a derivative of the malaria drug methylene blue, resurfaced again at AD/PD 2024, held March 5-9 in Lisbon, ...

The center accepts donations from residents of Sweden. Phenotypes collected include Alzheimer’s disease, family history of Alzheimer’s, cognitively normal, healthy normal, dementia with Lewy bodies, ...

13 Sep 2019. Marking the fall of the only remaining BACE inhibitor currently being tested for AD, Biogen and Eisai announced today the discontinuation of two Phase 3 studies of elenbecestat in people ...