Background There is a lack of international consensus on the optimal programme design to maximise benefits from pulmonary rehabilitation (PR). Aim To investigate the effect of 1) exercise modality and ...

Background Up to 50% of patients suffering acute pulmonary embolism (PE) demonstrate impaired pulmonary vascular recovery at follow up despite optimal anticoagulation, impacting negatively on ...

Methods Pre-clinical work captured clinically relevant extremes of respiratory parameters using a pediatric mannequin and mechanical ventilation. Biosensor data was compared to ventilator-measured ...

Results 256 day case MTs were analysed. Mean age was 72 years (34–86), 93 patients were male. 64 patients (25%) developed post procedure SE, and 4 of those had concurrent air leaks (due to lung ...

Introduction The number of computed tomography guided biopsies (CTGB) performed to investigate lung cancer is increasing. Data regarding performance and complications are important to inform patient ...

Results Of 190 participants included in the analysis, 153 (80%) had a positive response to mepolizumab [mean age at enrolment of 52±13 years, (59) 31% males]. Patients with positive mepolizumab ...

Introduction and Objectives Approximately 1 in every 4100 people worldwide are born with oesophageal atresia ± tracheo-oesophageal fistula (OA/TOF). Whilst surgical correction is, in most cases, ...

Background: Oxidative stress is thought to have a major role in the pathogenesis of airway obstruction. A study was undertaken to determine whether subjects with low levels of antioxidants (serum ...

The 2020 coronavirus pandemic has been particularly difficult for people living with chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD). COPD is associated with ...

Background Debate about the optimal lung cancer screening strategy is ongoing. In this study, previous screening history of the Dutch-Belgian Lung Cancer Screening trial (NELSON) is investigated on if ...

Background and objectives IgG4-related disease (IgG4-RD) is a multi-system fibro-inflammatory disorder originally described in association with autoimmune pancreatitis (AIP), usually but not always in ...

Background Although leukotriene receptor antagonists have an established role in the management of patients with chronic asthma, their efficacy in an acute asthma exacerbation is not fully known.