Aims To investigate the effect of succinic acid on the development of experimental autoimmune uveitis (EAU) and the underlying mechanism. Methods Succinic acid was administrated intraperitoneally to ...

Background To quantitatively assess outer retinal layers in eyes with hydroxychloroquine (HCQ) toxicity. Methods A retrospective case–control study was performed to identify eyes with HCQ ...

Background/Aims To investigate the efficacy of therapeutic soft contact lenses (SCLs) in gelatinous drop-like corneal dystrophy (GDLD) management. Methods This was a retrospective, consecutive, ...

The idea that a prolonged interval between diagnosing and treating uveal melanoma can affect prognosis has been at the centre of an active debate.1–5 This issue focuses on a key question for ...

Aim To examine the demographic and social factors associated with myopia in schoolchildren in Ireland. Methods Thirty-seven schools participated, representing a mix of urban and rural schools and ...

Aim: To report progression of primary angle closure suspects (PACS) to primary angle closure (PAC) at the 5 year follow up of a population based sample. Methods: 82 of 118 PACS who could be contacted ...

Aim To conduct a performance analysis of intra-arterial chemotherapy (IAC). Material and methods Comprehensive data search in MEDLINE from inception until December 2023. Peer-reviewed, ...

Background/aims Inherited retinal dystrophies (IRD) are a group of predominantly monogenic disorders which have genetically heterogeneous origins and display wide clinical phenotypic heterogeneity.

Aims To describe the distributions of and associations with intraocular pressure (IOP) and circumpapillary retinal nerve fibre layer (cRNFL) thickness in a population-based study. Methods Northern ...

All ophthalmologists will encounter patients presenting with an inherited retinal disease (IRD). Our clinical approach to IRDs has evolved over the last decade due to (1) improved and more accessible ...

Aims Conjunctival melanoma (CoM) is a rare but highly lethal ocular melanoma and there is limited understanding of its genetic background. To update the genetic landscape of CoM, whole-exome ...

Background Artificial intelligence (AI) in medical imaging diagnostics has huge potential, but human judgement is still indispensable. We propose an AI-aided teaching method that leverages generative ...