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《Nature Genetics》血液基因表达与剪接的多组学探秘
在生命科学的宏大拼图中,基因调控一直是一块关键却又充满神秘色彩的拼图碎片。通过全基因组关联研究(GWAS),科学家们发现了大量与常见疾病和复杂性状相关的遗传变异,然而,其中大多数位于非蛋白质编码序列,这使得这些基因型与表型之间的分子机制犹如隐藏在迷雾之中。为了穿透这层迷雾,深入了解基因调控的奥秘,来自多个研究机构的科研人员开展了一项意义重大的研究,相关成果发表在《Nature ...
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