Primary cilia play a powerful role in how cells sense their surroundings. They help guide embryo development and ensure ...

The leading causes of death in people with multiple myeloma include a weakened immune system, kidney failure, infections, and ...

A French civil servant functioned normally with 90 percent of his brain missing. How is this possible? Research reveals ...

CAR-T cell therapy has demonstrated remarkable success in treating hematologic malignancies and is now expanding into solid tumors.

New research shows that zeaxanthin, a plant-derived carotenoid, can strengthen the body's cancer-fighting immune cells and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. STING gain-of-function (GOF) mutations cause ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California 92037, United States Department of Molecular and Cellular Biology, The Scripps Research Institute, La ...