More information: Wanjie Wu et al, In vivo imaging in mouse spinal cord reveals that microglia prevent degeneration of injured axons, Nature Communications (2024). DOI: 10.1038/s41467-024-53218-0 ...

Symptoms from nerve compression may include pain, numbness or weakness that radiates into a limb. Surgery usually is not a ...

Spinal cord injury (SCI ... and were still present 10 days after injury. Activated microglia were also present 1–3 days after SCI, and the presence of both cell types correlated with areas ...

A key to their investigation was to elucidate the critical involvement of microglia in axonal degeneration post-spinal cord axon injury. Microglia are primary immune cells in the central nervous ...

In particular, astrocytes and microglia are the immunocompetent ... in rodents, using L5 spinal nerve ligation, a widely used animal model of neuropathic pain. Both MMP-9 and MMP-2, which are ...