Plasma protein binding is crucial for understanding pharmacokinetics, pharmacodynamics, and safety. However, it is often not considered to be a primary parameter for optimization in drug design. This ...

Organizations are using generative AI to stay ahead of the competition, but the real advantage lies in harnessing the power of your own data securely and at scale. SQL Server 2025, now in public ...

Saxitoxin (STX) is a lethal neurotoxin made by cyanobacteria and dinoflagellates associated with oceanic red tides. Its accumulation in seafood causes paralytic shellfish poisoning (PSP), a public ...

Objectives: Cell surface glycosylation can influence protein-protein interactions with particular relevance to changes in core fucosylation and terminal sialylation. Glycans are ligands for immune ...

Abstract: When building digital twins of existing technical solutions, we need a large amount of data on the parameters of their operation under various conditions. The source of data on the values of ...

Influenza A viruses originate from waterfowl. To become a human influenza virus, their hemagglutinin needs to adapt to bind human-type sialic acid receptors. Tight cell binding results from multiple, ...

Take advantage of parameter binding in ASP.NET Core 7 to convert request data to strongly typed parameters, improving both application performance and code maintainability. Minimal APIs are a type of ...

Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR 999077, China ...