During infection by HIV, three enzymes play essential roles in the life cycle of the virus. Reverse transcriptase (orange, top; PDB ID 3V4I) copies the viral RNA genome and makes a DNA copy. Integrase ...

Again, the selectivity of the inhibitory activity of AZT for a viral enzyme — HIV reverse transcriptase — compared with enzymes involved in DNA synthesis in normal cells provided a therapeutic ...

In the cytoplasm of the infected cell, genomic viral RNA is converted to double-stranded cDNA by the action of the viral reverse transcriptase. In the host cell nucleus, the viral enzyme integrase ...

The enzyme, called reverse transcriptase (RT), copies RNA molecules and changes them into complementary DNA duplicates that can then be inserted back into DNA, producing permanent sequence changes ...

It is an ester-derived prodrug that is converted in vivo by serum and tissue esterases to tenofovir, an acyclic nucleoside phosphonate (nucleotide) that inhibits HIV reverse transcriptase.

The following is a summary of “High-density lipoprotein anti-inflammatory capacity and acute kidney injury after cardiac and ...

The agreement includes licenses for the HiFi DNA Polymerase, HiTemp Reverse Transcriptase, HiRev Isothermal Polymerase and other enzymes that were in development directed towards genomics and ...

The agreement includes licenses for the HiFi DNA Polymerase, HiTemp Reverse Transcriptase, HiRev Isothermal Polymerase and other enzymes that were in development directed towards genomics and ...

Non-exclusive license includes HiFi DNA Polymerase, HiTemp Reverse Transcriptase, HiRev Isothermal Polymerase and other enzymes for genomics and diagnostic applications REDWOOD CITY, Calif., Oct. 01, ...