Retinoic acid, a vitamin A derivative, has long been used as a treatment in certain cases of neuroblastoma — but its effects vary depending on the disease context. While the drug has minimal impact on ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10 ...

(L to R) Co-first and co-corresponding author Min Pan, PhD, co-first author Yinwen Zhang, PhD, St. Jude Department of Computational Biology, co-corresponding author John Easton, PhD, St. Jude ...

Researchers demonstrate how the co-exposure of bisphenol A and retinoic acid (RA) potentiate the effect of RA signaling in early development. Synthetic chemicals and plastics are useful and ...

Arsenic Trioxide and All-Trans Retinoic Acid Combination Therapy for the Treatment of High-Risk Acute Promyelocytic Leukemia: Results From the APOLLO Trial In the article that accompanies this ...