Here are six things to know about the Florida Python Challenge: When is the 2025 Florida Python Challenge? It begins at 12:01 a.m. on July 11, 2025 and it ends at 5 p.m. on July 20, 2025.

The annual Florida Python Challenge is underway and concludes Aug. 18. Professional python trapper Brandon Rahe writes that native species, and indeed the entire Everglades ecosystem, would probabl… ...