Lonijaposides O–W have structural features that involve amino acid units sharing the N atom with a pyridinium (1 – 5) or nicotinic acid (6 – 9) moiety. The absolute configurations of the amino acid ...

Nicotinic receptors — a family of ligand-gated ion channels that mediate the effects of the neurotransmitter acetylcholine — are among the most well understood allosteric membrane proteins ...

Main The nicotinic acetylcholine (ACh) receptors have been objects of attention since Claude Bernard investigated the action of a Central American arrow poison (CURARE).

Assays of human postmortem brain tissue have revealed that smokers have greater densities of high-affinity nicotinic acetylcholine receptors (nAChRs) in several brain regions than do nonsmokers or ...

Weak partial agonists that promote a desensitized state of the α7 nicotinic acetylcholine receptor (nAChR) have been associated with anti-inflammatory effects. Exemplar compounds feature a tertiary or ...

I Tried the Trendy New Fatty Acid From Fatty15—Here’s What I Thought If you're interested in learning about pentadecanoic acid, look no further. Healthy young woman taking supplements ...

Objective—To determine the mechanisms by which extended-release nicotinic acid reduces circulating lipoprotein (a) concentrations in hypertriglyceridemic patients. Approach and Results—Eight ...