New research shows that an experimental drug fine-tuned to a specific pain pathway can ease post-surgery aches, a finding that may eventually offer an alternative to highly addictive opioids.

A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to ...

NEWS 14 October 2022 New non-opioid pain drug pushes through to pivotal trials Could Vertex’s Nav1.8 blocker tap the elusive analgesic potential of voltage-gated sodium channels?

This new nonaddictive alternative is the first of its kind that interrupts the pain signal before it reaches the brain.

Journavx is the first truly new painkiller approved by the Food and Drug Administration in more than 20 years. But the drug is expensive, and many people can't get it yet.

A new molecule acts like a local, long-lasting anesthetic, providing robust pain relief for up to three weeks.

The medication initially known as VX-548 blocks sodium channels in nerves, blocking pain signals before they reach the brain ...

Peripheral neuropathy treatment options Even in instances where neuropathy can't be fully reversed, finding and treating the underlying cause can mitigate symptoms, our experts agree.

Millions of people around the world suffer from chronic low back pain, often finding relief only through temporary solutions like painkillers or invasive surgeries. However, groundbreaking ...

Pain is one of the most debilitating symptoms that presents with neuropathy. Neuropathic pain syndrome is a challenge to treat and, even with appropriate evidence-based treatment, only a 40% ...

A new kind of pain medication has been approved for sale by the Food and Drug Administration. It is being touted as an alternative to opioids. It works differently, and it is not addictive. NPR's ...

Early clinical trial results suggest that a groundbreaking new antibiotic drug could be a “massive game changer” for some patients suffering from chronic lower back pain.