the mouse has become the model of choice. Here the authors re-examine the value of this mouse model as a tool for understanding human diabetes and for testing potential therapies, reviewing both ...

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's ...

Selecting an appropriate mouse model is one of the most important decisions a pre-clinical researcher can make. Which is best suited for immuno-oncology? Cancer research and drug discovery has ...

The global humanized mouse model market is projected to be valued at USD 101.5 million in 2023 and is expected to grow at a ...

Every year, over 1.5 million new cases of prostate cancer are diagnosed throughout the world. As one of the leading causes of ...

They created a mouse model that recapitulates the early non-motor symptoms as well as the motor difficulties in Parkinson's disease in a manner that directly mimics the condition in many patients.

Scientists from the Cardiovascular Research Center at the University of Virginia School of Medicine and Astrazeneca plc have developed a new mouse model of cardiovascular disease associated with ...

Our objective was to create a mouse model to determine if PNLIP p.T221M causes CP and to define the mechanism. Design We created a mouse model of Pnlip p.T221M and characterised the structural and ...