The success and pathogenicity of HIV-1 largely resides in the function of the viral protein Nef. Here, the authors propose that Nef modulates a T cell's ability to form an immunological synapse ...

Multiplexed detection of viral nucleic acids is important for rapid screening of viral infection. In this study, we present a molybdenum disulfide (MoS2) nanosheet-modified dendrimer droplet ...

An analysis of the rate of different nucleotide substitutions in clinical samples in the RT and PR regions of patients harboring subtype-B HIV-1 viruses.

Immuno Cure BioTech, a clinical-stage biotechnology group based in Hong Kong Science Park, announced its upcoming collaboration with PharmaJet to evaluate the safety and immunogenicity of HIV ...

HiCapR uncovers HIV RNA homodimers and long-range interactions that show structural dynamics critical for viral packaging and assembly.

The N-heptad repeat (NHR) of the HIV-1 gp41 prehairpin intermediate (PHI) is an attractive potential vaccine target with high sequence conservation across diverse strains. However, despite the potency ...

FRIDAY, June 20, 2025 (HealthDay News) — A new shot to prevent HIV infection has just been approved — and it only needs to be taken twice a year.

ICVAX employs Immuno Cure's patented PD-1-Enhanced DNA Vaccine technology, which aims to achieve sustained, immune-mediated HIV-1 virological control without the need of ART.

Under the terms of the agreement, Immuno Cure will use PharmaJet’s Tropis ID system in a human clinical trial to deliver their novel HIV-1 therapeutic DNA Vaccine (ICVAX).

编辑推荐： 本研究针对HIV-1潜伏库量化难题，创新性地将完整前病毒DNA检测技术 (IPDA)适配至芯片数字PCR (dPCR)平台，采用CCR5替代传统RPP30作为参考基因，系统评估了其在HIV-1不同亚型中的检测效能。结果表明该技术显著减少操作时间，在ART治疗者中实现高特异性检测，为非B亚型样本的精准量化提供 ...

BENNINGTON — The AIDS Project of Southern Vermont (APSVT) will participate in the nation’s largest coordinated National HIV Testing Day event by offering FREE rapid HIV and hepatitis C testing and ...

After incorporating the DNA of HIV-1 into the genome of every tissue of the animals' bodies, the team found it could delete targeted fragments of HIV-1 from the genome in most tissues.