High-dose 8.0 mg aflibercept injections can extend treatment intervals while helping to significantly reduce central subfield thickness (CST) and maintain stable best-corrected visual acuity (BCVA) in ...

Abstract and Introduction Abstract Background High dose oral thiamine may have a role in treating diabetes, heart failure, and hypermetabolic states. The purpose of this study was to determine the ...

Thiamine requirements are related to energy metabolism; specifically, 0.33 mg of thiamine are required for every 4400 kJ of energy. For adults the DRI of thiamine is between 1.1 and 1.4 mg per day.

Research efforts in FLASH radiotherapy (FLASH-RT) have increased at an accelerated pace recently. FLASH-RT involves ultra-high dose rates and has been shown to reduce toxicity to normal tissue while ...

The patient received the gene therapy on Nov. 5 and subsequently showed signs of systemic hyperinflammatory syndrome, a condition seen in some people who receive high, systemic doses of AAV.

Among babies who’d never received SMA treatments (treatment-naïve), the high-dose therapy was also associated with a reduced risk of death, hospitalization, and serious respiratory outcomes, as well ...

An abundance of Faecalibacterium prausnitzii or Roseburia hominis may predict the effectiveness of high-dose thiamine treatment to alleviate chronic fatigue in quiescent inflammatory bowel disease ...

In one small preliminary study, high doses of thiamine reduced chronic fatigue, which may be mediated by alterations in the gut microbiota. The current study further assessed the role of the gut ...

Thiamine (vitamin B1) is a water-soluble vitamin that helps the growth and function of your body's cells. It's needed for a healthy liver, skin, eyes, hair, and brain. It's also thought to help ...

Treatment of beriberi focuses on restoring the body’s thiamine levels. Typically this requires receiving high doses of thiamine intravenously (through an IV) at first. Later on, oral supplements can ...

To be eligible, psychedelic treatment (including MDMA, LSD, psilocybin, or ayahuasca) had to be given orally with no additional use of antidepressants, while escitalopram trials had to compare at ...