2025 Week 1 NFL picks, odds, best bets by proven model: This 5-way football parlay could return around 25-1 After 10,000 simulations, SportsLine's model reveals its top Week 1 NFL 25-1 football parlay ...

Before finalizing your 2025 Fantasy football draft strategy, be sure to check out the 2025 Fantasy football rankings and cheat sheets from the proven computer model at SportsLine.