Glutamate uptake via EAATs serves as a major mechanism for regulating the extracellular concentration of glutamate and preventing glutamate excitotoxicity. Glutamate uptake is mainly accomplished by ...

Butovsky believes xenon has potential as an AD treatment. A Phase 1 clinical trial of xenon at BWH is recruiting healthy elderly volunteers to test safety and effects on immune cells. “I hope this ...

VRAC plays a dual role in ischemia-reperfusion injury: on the one hand, activated VRAC promotes the release of intracellular chloride and glutamate, exacerbating cellular swelling and excitotoxicity, ...

6 Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia Correspondence to Associate Professor Steve Vucic, Sydney Medical School Westmead, University of ...

but especially something called glutamate excitotoxicity, where a level of a particular neurotransmitter in the brain called glutamate can rise to a level 100 times its baseline. “We see high ...

Newly discovered estrogen receptor-dependent signaling pathways demonstrate that estrogen functions in the cytosol as well as in the nucleus. The classic estrogen receptor signaling pathway occurs ...

1 University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK 2 Department of Neurology, North Bristol Trust, Frenchay Hospital, Bristol, UK 3 Department Neurology, ...

Department of Neurology and Brain Research Institute, Geffen School of Medicine at UCLA, and VA Greater Los Angeles Health Care System, Los Angeles, CA 90073, USA ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...

Patients with ICH had high levels of excitatory and inflammatory molecules such as glutamate ... These findings suggested that inflammation and excitotoxicity could play a role in secondary ...

New research identifies key cellular mechanism driving Alzheimer's disease The breakthrough marks a promising target for drug therapies that slow, possibly reverse, the disease's development Date: ...