Cancer dysregulates the complex structure of tissues and internal cellular pathways. As a result, the immune system loses its ability to effectively target tumor cells. The immune system is made up of ...

The glycocalyx surrounds each cell in the human body like a coat. This complex sugar layer plays a key role in the progression of numerous diseases, such as cancer and autoimmune diseases. The ...

Cell biology is a world of constant motion and hidden structures. Much of what we know about cells comes from decades of research using microscopes, stains, and models. Yet, even in this well-charted ...

Holly has a degree in Medical Biochemistry from the University of Leicester. Her scientific interests include genomics, personalized medicine, and bioethics. Imagine you open up the hood of your car ...

A previously unknown structure discovered in our cells could pave the way toward new treatments for various genetic disorders. The existence of the organelle—which has been dubbed the "hemifusome"—was ...

Abstract: Immunomechanobiology, the study of how physical forces influence the behavior and function of immune cells, is a rapidly growing area of research. It is becoming increasingly recognized that ...

Bispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed ...

It is well established that cellulose synthesis in higher plants requires three different but related cellulose synthase (CESA) isoforms. Here the authors provide convincing biochemical and cryo ...

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles. These hormones not only influence the body, but can cross into the brain and shape the behavior ...

Despite clinical and scientific advancements, heart failure is the major cause of morbidity and mortality worldwide. Both mitochondrial dysfunction and inflammation contribute to the development and ...

In her new book, “The Ideological Brain,” the neuroscientist Leor Zmigrod outlines what makes some people prone to rigid thinking. “Ideologies numb our direct experience of the world,” Leor Zmigrod, a ...