Researchers engineered and screened dozens of base editors to precisely target a single mutation without editing other portions of the DNA.

Researchers used evolutionary genetics and CRISPR gene editing tech to develop an innovative treatment for gout. The approach ...

91%客观缓解率的背后，是CRISPR基因编辑技术对免疫细胞"同族相残"魔咒的彻底打破 在全球细胞治疗领域因CAR-T在B细胞血液肿瘤中的成功而欢呼时，一个顽固的堡垒依然久攻不下——T细胞恶性肿瘤。当患者自身的T细胞已成为“叛军”，如何再用它们制造“平叛军队”？即使造出军队，它们是否会在执行任务前就“自相残杀”？ 美国生物科技公司Wugen用一项突破性的技术设计和1.15亿美元的最新融资，给出了自 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Synovial sarcoma (SySa) is an aggressive soft ...

What if a heart attack and lifetime of statin drugs could be avoided with a one-time, two-hour infusion? Kiran Musunuru, a University of Pennsylvania cardiologist and leading gene-editing researcher, ...

CRISPR Therapeutics is a biotech company that borrows its name from the groundbreaking gene editing technology CRISPR. As of last year, the company has earned FDA approval for a CRISPR-based treatment ...

CRISPR Therapeutics has reported reductions in triglycerides and LDL cholesterol of more than 80% after a single dose of its in vivo liver editing prospect CTX310, encouraging the company to forge ...

For researchers working at the forefront of biology, the pressure to publish groundbreaking findings is intense. Understanding disease mechanisms, developing new therapies, and making discoveries ...

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason ...

The gene-editing technique known as CRISPR is promising to revolutionize medicine. Some researchers are trying to help make it available for people with very rare genetic disorders. A gene-editing ...