Highly pathogenic avian influenza A(H5N1) viruses have caused widespread infections in dairy cows and poultry in the United ...

A 14-year-old patient presented to the ED with a 12-month history of joint pains and a 2-month history of headaches and ...

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for myelofibrosis. Driver mutations are the pathophysiological hallmark of the disease, but the role of mutation ...

Talquetamab is a T-cell–redirecting bispecific antibody targeting G protein–coupled receptor class C group 5 member D (GPRC5D). 13-15 In the MonumenTAL-1 study, more than 71% of the patients ...

New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

What left ventricular ejection fraction (LVEF) range is a component of the contemporary definition of heart failure with preserved ejection fraction? The current nomenclature defines heart failure ...

Multiple diseases in children have been linked to manufactured synthetic chemicals, which are subject to few legal or policy constraints. A revamping of law and restructuring of the chemical ...

This is a retrospective study of the history, roentgenology and autopsy pathology when appropriate of all infants with severe respiratory-distress syndrome who required twenty-four hours or more ...

The Race and Medicine collection reflects NEJM’s commitment to understanding and combating racism as a public health and human rights crisis. Our commitment to antiracism includes efforts to ...

Dr. Annie Liu (Medicine): A 35-year-old woman was admitted to this hospital because of shortness of breath and edema in the legs. Eight weeks before the current presentation, the patient was ...

Currently approved triglyceride-lowering medications provide minimal benefit for patients with persistent chylomicronemia. New research findings on plozasiran, a small interfering RNA, are ...