Cardiac fibroblasts (CF) can become activated and produce excessive extracellular matrix, contributing to fibrotic remodeling ...

Cardiovascular disease remains a leading cause of morbidity and mortality in adults despite recent scientific advancements.

Patients with an autoimmune or inflammatory disease (AIID) are at increased cardiovascular risk and may benefit more from statin therapy. In the FOURIER trial (Further Cardiovascular Outcomes Research ...

Driving the future of cardiovascular diagnosis and disease management through investigations of clinical genetics and the novel application of precision medicine ...

The growing morbidity, mortality, and health care costs related to heart failure (HF) underscore the urgent need to prioritize its primary prevention. Whereas a risk-based approach for HF prevention ...

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...

High-volume physical activity (PA) is associated with a higher prevalence of subclinical coronary artery disease (CAD). However, the clinical significance of subclinical CAD among high-volume ...

An official, Open Access journal of the American Heart Association and the Society of Vascular and Interventional Neurology ...

Current guidelines suggest engaging in a minimum of 150 minutes of moderate to vigorous physical activity (MVPA) each week to support overall health. However, the effect of concentrated versus evenly ...

Department of Cardiology, The Second Affiliated Hospital (M.Z., Z.T., N.W., Y.Z., D.W., X.W., P.W., Q.Y., Y.K., M.W., J.C., Z.W., M.C., L.L., Y.L., J.T., B.Y ...

High-quality mechanistic and clinically relevant science to keep clinicians at the forefront of the latest advancements in the diagnosis and treatment of heart failure ...