Introduction Fluoroquinolones can cause severe collagen-associated adverse effects, potentially impacting the pulmonary ...

The mechanism of thrombocytopenia during acute pulmonary hypertension (PH) decompensation may be partly due to platelet aggregation in the lung. Platelet aggregates in explanted lung from 16 lung ...

A structural and metabolic framework for classifying pre-clinical tuberculosis infection phenotypes using 18F-FDG PET-CT: a prospective cohort analysis following M. tuberculosis exposure ...

4 Department of Respiratory Medicine, Royal Prince Alfred Hospital, Sydney, Australia Correspondence to: Dr D Breen, Intensive Care Unit, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW ...

Intensive Care Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK Correspondence to: Dr C S Garrard, Intensive Care Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK; chris.garrard{at}clinical-medicine ...

The study of patients being weaned from mechanical ventilation has offered new insights into the physiology of respiratory failure. Assessment of the balance between respiratory muscle strength, work ...

Guidelines on contraindications for lung function tests have been based on expert opinion from >30 years ago. High-risk contraindications to lung function testing are associated with cardiovascular ...

1 Respiratory Cell and Molecular Biology, Division of Infection, Inflammation and Repair, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK 2 Department of Molecular ...

1 Centre for Respiratory Failure and Sleep Disorders, Royal Prince Alfred Hospital, Sydney, NSW 2050 and Institute of Respiratory Medicine, University of Sydney, NSW 2006, Australia 2 Human Nutrition ...

2 Guy's and St Thomas' Foundation NHS Trust, London, UK 3 Greenwich Primary Care Trust, London, UK 4 Croydon Primary Care Trust, London, UK Background The COPD (chronic obstructive pulmonary disease) ...

2 Department of Pulmonary and Cardiac Rehabilitation, Coventry University, School of Health and Life Sciences, Coventry, UK 3 Clinical Trials Unit, Warwick Medical School, The University of Warwick, ...

BACKGROUND Patients with cystic fibrosis (CF) have significantly decreased plasma concentrations of nutrient antioxidant vitamins, especially of β-carotene, which is thought to result from fat ...