Clooney and Wyle, who played Doug Ross and John Carter, respectively, starred alongside each other on the hit medical drama for five seasons before Clooney exited the series to focus on other acting endeavors. Wyle continued with the show through season 11, making guest appearances in seasons 12 and 15. ER ran from 1994 to 2009.

George Clooney is sending Noah Wyle his praises for his work on The Pitt. The former ER co-stars have remained friends since working on the NBC medical drama, and while appearing on Late Night with Seth Meyers,