Lodolo made back-to-back starts against the Cubs in May. May 25 in Cincinnati, the Cubs scored three runs in five innings against him, including a home run by Reese McGuire (that was McGuire’s two-homer Cubs debut). May 31 at Wrigley Field, Lodolo threw six shutout innings.

SPLITTING THE DIFFERENCE: This is the 23rd of the Cubs’ 37 series in which they have split the first two games. There was no third game in two series. In the others, the Cubs are 11-9 overall but 3-4 at home, including 2-2 after winning, then losing in the first two games. They 4-0 after winning and losing on the road. (Courtesy BCB’s JohnW53)

The Baltimore Orioles (50-60) visit the Chicago Cubs (64-45) Saturday for the second game of their 3-game series. First pitch from Wrigley Field is set for 2:20 p.m. ET (FS1). Let's analyze BetMGM Sportsbook's MLB odds around the Orioles vs. Cubs odds and make our expert MLB picks and predictions for the best bets.