Microsoft today announced the public preview of Python in Excel, which will allow advanced spreadsheet users to combine scripts in the popular Python language and their usual Excel formulas in the ...

Some members of the Microsoft 365 Insiders program can now try out the combination of Python, Excel and the Anaconda Python repository.

Starting in January 2025, Microsoft began the process of introducing Python in Excel for the web, a sign of the company's intent to continue rolling out more advanced analytics tools in the coming ...

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Writing 100k rows at a time should be fine, so I could write to the file once for each parameter combination.