Cell division is one of the most thoroughly studied processes in biology, yet many of its details remain mysterious. A century-old puzzle surrounding the "crown" of cell division—the kinetochore ...

A protein known as MPS1 helps to ensure that a key process during cell division of oocytes—unfertilized egg cells—occurs in a ...

The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...

In 2000, researchers discovered that mutations that inactivate a gene known as TRIM37 cause a developmental disease called ...

“We closed a gap in our knowledge that was open for 10 years,” says Duccio Conti, a postdoc in the Musacchio group and first author of the publication. In healthy DNA replication, at first, each new ...

This video of a so-called HeLa cell dividing demonstrates how sensitive the cell division process is. While all is going well at the beginning of the video, as the clip nears its end you can see the ...

TRIM37, the researchers found, is critical in preventing extra spindle poles from forming, which obstructs normal cell ...

CAPTION: (Top) Condensins seem to act as a molecular crosslinkers to make loops. (Bottom, left) Condensins (red) locate around chromosome center. (Bottom, right) Nucleosomes around the periphery ...